← Research ProtocolsMOTS-C
STUDIED EXPOSURE MAP / 2021
MOTS-C
tested in research.
The actual doses, concentrations or exposure levels reported by the source — kept attached to route, population, timeframe and evidence type.
TRANSLATIONAL / HUMAN SAMPLING + MOUSE DOSINGNATURE COMMUNICATIONSSTUDIED EXPOSURE ≠ RECOMMENDED DOSE
STUDIED EXPOSURE / SOURCE DATANumbers below describe this research source only.
5 mg/kg/day
IP · mouse model
15 mg/kg/day
IP · mouse model
Context: Humans in this paper were not given exogenous MOTS-c. Human participants were sampled around exercise; the displayed administered doses are from mice.
NOT A DOSING GUIDEENHANCED is reporting what researchers administered or tested. It does not convert these numbers into a personal dose, reconstitution plan, cycle, titration schedule or recommendation.
SOURCE / NATURE COMMUNICATIONS
MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
Study design and tested exposure are separated from recommendation. Route and population stay visible so the numbers cannot be read without context.
2021
01 / DESIGNTranslational study with mouse intervention experiments and human exercise sampling
02 / POPULATION / MODELMouse models; human arm measured endogenous MOTS-c around exercise
03 / ROUTEIntraperitoneal in mouse intervention experiments
04 / TIMEFRAMEDaily mouse exposure in selected experiments
05 / PRIMARY QUESTIONPhysical-performance biology and endogenous exercise response
It supports a factual statement about the exposure tested in this research source. It does not establish that the same exposure is appropriate, effective or safe outside that source.
Mitochondrial-derived peptide research
Study exposure ≠ personal protocol. Animal doses are never converted to human-equivalent amounts here. IV, topical, oral, intranasal and subcutaneous exposures are not treated as interchangeable.