← Research Protocols5-Amino-1MQ
STUDIED EXPOSURE MAP / 2018
5-Amino-1MQ
tested in research.
The actual doses, concentrations or exposure levels reported by the source — kept attached to route, population, timeframe and evidence type.
PRECLINICAL / MOUSEBIOCHEMICAL PHARMACOLOGYSTUDIED EXPOSURE ≠ RECOMMENDED DOSE
STUDIED EXPOSURE / SOURCE DATANumbers below describe this research source only.
20 mg/kg/injection
SC · three times daily · 11 days
10–150 mg/kg/day
initial mouse dose-escalation range
Context: 5-Amino-1MQ is a small-molecule NNMT inhibitor, not a peptide. The displayed exposures are mouse data; no human dose is inferred.
NOT A DOSING GUIDEENHANCED is reporting what researchers administered or tested. It does not convert these numbers into a personal dose, reconstitution plan, cycle, titration schedule or recommendation.
SOURCE / BIOCHEMICAL PHARMACOLOGY
Selective and membrane-permeable NNMT inhibitors reverse high-fat-diet-induced obesity in mice
Study design and tested exposure are separated from recommendation. Route and population stay visible so the numbers cannot be read without context.
2018
01 / DESIGNDiet-induced-obesity mouse study with dose escalation and treatment cohort
02 / POPULATION / MODELDiet-induced obese mice · no published human dosing study
03 / ROUTESubcutaneous · three injections/day
04 / TIMEFRAME11 days
05 / PRIMARY QUESTIONBody weight and metabolic effects in mice
It supports a factual statement about the exposure tested in this research source. It does not establish that the same exposure is appropriate, effective or safe outside that source.
Nicotinamide N-methyltransferase (NNMT) research
Study exposure ≠ personal protocol. Animal doses are never converted to human-equivalent amounts here. IV, topical, oral, intranasal and subcutaneous exposures are not treated as interchangeable.